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What is ALDACTONE?
- ALDACTONE contains Spironolactone which belongs to a group of medicines called potassium-sparing diuretics (water tablets), which help you lose excess fluid from your body
CONSUMER MEDICINE INFORMATION
THERAPEUTIC USES
WARNING & PRECAUTIONS
INTERACTIONS
DIRECTIONS FOR USE
SIDE EFFECTS
MORE INFORMATION
What ALDACTONE is used for?
ALDACTONE is used to treat,
- congestive heart failure
- nephrotic syndrome (a kidney disorder)
- liver cirrhosis with fluid retention (oedema) and swelling of the abdomen (ascites)
- a cancerous disease with swelling of the abdomen (malignant ascites)
- or diagnose primary aldosteronism (a condition where excess hormone is produced)
Talk to your doctor before taking this medicine, if you:
- are allergic to spironolactone or any of the other ingredients in this medicine
- have diabetes
- have Addison’s disease (weakness, loss of energy, low blood pressure and dark pigmentation of the skin)
- have kidney problems which may be severe or worsening
- have high blood levels of potassium
- have a diet high in potassium
- have low blood levels of sodium
- have liver cirrhosis
- have been passing small amounts of urine
- have an inherited disorder of the red blood pigment haemoglobin causing skin blisters, abdominal pain and nervous system disorders (porphyria)
- have abnormal periods or swollen breasts
Tell your doctor if you are taking,
- blood pressure lowering medicines such as captopril or enalapril, valsartan or losartan
- chlorpropamide (used in diabetes)
- digoxin (used in some heart conditions)
- ciclosporin or tacrolimus (used to prevent organ transplant rejection, treat rheumatoid arthritis, eczema or psoriasis)
- fludrocortisone (a corticosteroid)
- warfarin (used to thin the blood)
- other potassium-sparing diuretics
- lithium (used for some mental illnesses)
- indomethacin and mefenamic acid used for pain
- potassium supplements (potassium salts)
- noradrenaline (norepinephrine) (used for low blood pressure or heart problems)
- an anaesthetic
- carbenoxolone (an ulcer healing drug)
- trimethoprim and trimethoprim-sulfamethoxazole used as antibiotic
- Always take this medicine exactly as your doctor has told you
- Swallow the tablet with water
Adults
- Congestive heart failure – 100mg a day. The maintenance dose is 25-200mg a day. In difficult or severe cases, up to a maximum of 400mg a day may be taken
- Nephrotic syndrome – 100-200mg a day
- Liver cirrhosis with fluid retention and swelling of the abdomen – 100-400mg a day. Your doctor will decide on the best maintenance dose for you
- A cancerous disease with swelling of the abdomen – 100-200mg a day. In severe cases, up to a maximum of 400mg a day may be taken
- Primary aldosteronism diagnosis – Long test: 400mg a day for 3-4 weeks. Short test: 400mg a day for 4 days
- Primary aldosteronism treatment – 100-400mg a day in preparation for surgery
Children
- Usual starting dose is 3mg per kg of body weight a day, to be taken in divided doses. Your doctor will adjust the dose depending on the response to treatment
If you take more ALDACTONE
- If you take more ALDACTONE at the same time, contact your nearest hospital casualty department or tell your doctor immediately
- Symptoms of an overdose include drowsiness, mental confusion, dizziness, diarrhoea, decreased blood levels of sodium, increased blood levels of potassium (symptoms include ‘pins and needles’ or tingling, unusual tiredness or weakness, muscular weakness, paralysis with a loss of muscle tone, muscle spasm)
If you forget to take ALDACTONE
- If you forget to take a dose, take it as soon as you remember it and then take the next dose at the right time
- Do not take a double dose to make up for a forgotten dose
If you stop taking ALDACTONE
- Consult your doctor before you stop taking ALDACTONE
Like all medicines, ALDACTONE can cause side effects, although not everybody gets them.
SERIOUS
COMMON
UNCOMMON
RARE
VERY RARE
- high blood levels of potassium (muscle twitching or weakness, irregular heartbeat, unusual tiredness or weakness, paralysis with or without loss of muscle tone, circulatory failure), especially if you have impaired kidney function or a diet high in potassium
- an allergic reaction such as swelling of the face, lips, tongue or throat, difficulty breathing or swallowing, shock, collapse, skin rash or itching
- severe form of skin rash with flushing, fever, blisters or ulcers (Stevens-Johnson syndrome)
- increased bruising, nosebleeds, sore throats or infections
- low blood levels of sodium, changes in the levels of chemicals in the body
- lack of muscle control or coordination, drowsiness, dizziness, headache, clumsiness tiredness, confusion
- impaired liver function, a poisonous effect on the liver
- stomach upset, inflammation of the stomach lining, bleeding in the stomach, stomach or intestinal ulcers, stomach cramps, diarrhea
- bone softening due to vitamin D deficiency, leg cramps
- acute kidney failure particularly in those who already have impaired kidney function
- enlarged breasts in men, changes in voice pitch, reduced sexual potency in men, decreased sexual ability/drive, breast tenderness, breast lumps and increased hair growth in females, irregular periods, sweating
Disclaimer:
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
