What AMITONE 10MG is used for?

It is used to treat:

• Depression in adults (major depressive episodes)
• Neuropathic pain in adults
• Chronic tension type headache prophylaxis in adults
• Migraine prophylaxis in adults
• Bed-wetting at night in children aged 6 years and above, only when organic causes, such as spina bifida and related disorders

Tell your doctor about any other medicine you are taking:

• monoamine oxidase inhibitors (MAOIs) e.g. phenelzine, iproniazid, isocarboxazid, nialamide or tranylcypromine (used to treat depression) or selegiline (used to treat Parkinsons disease)
• adrenaline, ephedrine, isoprenaline, noradrenaline, phenylephrine and phenylpropanolamine (these may be present in cough or cold medicine, and in some anaesthetics)
• medicine to treat high blood pressure for example calcium-channel blockers (e.g. diltiazem and verapamil), guanethidine, betanidine, clonidine reserpine and methyldopa
• anticholinergic drugs such as certain medicines to treat Parkinsons disease and gastrointestinal disorders (e.g. atropine, hyoscyamine)
• thioridazine (used to treat schizophrenia)
• tramadol (painkiller)
• medicines to treat fungal infections (e.g. fluconazole, terbinafine, ketoconazole, and itraconazole)
• sedatives (e.g. barbiturates)
• antidepressants (e.g. SSRIs (fluoxetine, paroxetine, fluvoxamine), and bupropion)
• medicines for certain heart conditions (e.g. beta blockers and antiarrhythmics)
• cimetidine (used to treat stomach ulcers)
• methylphenidate (used to treat ADHD)
• ritonavir (used to treat HIV)
• oral contraceptives
• rifampicin (to treat infections)
• phenytoin and carbamazepine (used to treat epilepsy)
• Johns Wort (hypericum perforatum) a herbal remedy used for depression
• thyroid medication
• medicines to treat irregular heartbeats (e.g. quinidine and sotalol)
• astemizole and terfenadine (used to treat allergies and hay fever)
• medicines used to treat some mental illnesses (e.g. pimozide and sertindole)
• cisapride (used to treat certain types of indigestion)
• halofantrine (used to treat malaria)
• methadone (used to treat pain and for detoxification)
• diuretics (water tablets e.g. furosemide)

• Always take this medicine exactly as your doctor has told you
• AMITONE 10MG can be taken with or without food
• Swallow the tablets with a drink of water. Do not chew or crush them

For Depression

Adults

• The recommended initial dose is 25 mg two times daily
• Depending on your response to the medicine, your doctor may gradually increase the dose to 150 mg per day divided in two doses

Elderly (above 65 years of age) and patients with cardiovascular disease

• The recommended initial dose is 10 mg 25 mg daily
• Depending on your response to the medicine, your doctor may gradually increase the dose to a total daily dose of 100 mg divided in two doses

For Neuropathic pain, chronic tension type headache and migraine prophylaxis

Adults

• The recommended initial dose is 10 mg - 25 mg in the evening
• The recommended daily dose is 25 mg - 75 mg
• If you receive doses above 100 mg daily, your doctor may need to do more frequent follow-up with you

Elderly (above 65 years of age) and patients with cardiovascular disease

• The recommended initial dose is 10 mg 25 mg in the evening
• If you receive doses above 75 mg daily, your doctor may need to do more frequent follow-up with you

Bed-wetting at night:

The recommended doses for children:

• aged 6 to 10 years: 10 mg 20 mg daily. A suitable dosage form should be used for this age group
• aged 11 years and above: 25 mg 50 mg

If you take more AMITONE 10MG

• If you take more AMITONE 10MG or if someone else has taken your medicine, talk to your doctor immediately and you may need Medical attention

If you forget to take AMITONE 10MG

• If you forget to take a dose, take it as soon as you remember, unless it is time for your next dose
• Do not take a double dose to make up for a forgotten dose

If you stop taking AMITONE 10MG

• Do not stop taking AMITONE 10MG without talking to your doctor