AMLOKIND H Tablet is used in the treatment of hypertension (high blood pressure)

AMLOKIND H Tablet may also be prescribed for other conditions as determined by your doctor.

• Amlodipine Besylate belongs to a group of medicines known as calcium channel blockers. Amlodipine Besylate prevents the calcium from moving into the blood vessel wall thereby preventing tightening of blood vessel walls. This reduces the blood pressure and improves symptoms of chest pain.

• Hydrochlorothiazide belongs to group of medicines called thiazide diuretics also known as water tablets. It removes excess fluid by making the kidney produce more urine, thereby reducing the blood pressure.

AMLOKIND H Tablet act additively to reduce the blood pressure.

• The dosage of oral tablets of AMLOKIND H Tablet depends on the age, weight and medical condition of an individual. Take AMLOKIND H Tablet as prescribed by your doctor.
• You must swallow the tablet with a glass of water. Do not chew the tablet.
• Take your daily dose at same time (preferably at breakfast).
• Do not take the tablet with grapefruit juice (it can lead to increase in amlodipine concentration which would increase the lowering of the blood pressure).
• AMLOKIND H Tablet is not recommended for children and adolescent under 18 years of age.
• Do not discontinue the medication without consulting a doctor.
• If you miss a dose of AMLOKIND H Tablet, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

If you have taken an overdose of AMLOKIND H Tablet, please contact your doctor immediately.

Symptoms of overdose of Amlodipine may include the following:

• Dizziness
• Light headedness
• Fainting, weakness
• Cool and clammy skin
• Hypotension (low blood pressure)
• Loss of consciousness

Symptoms of overdose of Hydrochlorothiazide may include the following:

• Dehydration
• Diarrhoea or constipation, abdominal pain
• Dizziness, fainting
• Electrolyte imbalance (hypokalaemia (low levels of potassium in blood), hypochloraemia (low levels of chloride ions in blood, hyponatremia (low levels of sodium in the blood)
• Lethargy
• Nausea
• Weakness

Drugs that interact with Amlodipine Besylate:

• Cyclosporin, Tacrolimus
• Dantrolene
• Diltiazem, Verapamil
• Grapefruit
• Ketoconazole, Itraconazole
• Rifampicin, Erythromycin, Clarithromycin
• Ritonavir, Indinavir, Nelfinavir
• Simvastatin
• St Johns wort

Drugs that interact with Hydrochlorothiazide:

• Adrenaline
• Alcohol
• Amantadine
• Aminoglycoside antibiotics
• Atropine, Biperiden
• Barbiturates
• Cholestyramine, Colespitol
• Corticosteroids
• Cytotoxic drugs
• Insulin, Oral anti-diabetic drugs
• Lithium
• Narcotic drugs
• NSAIDs (non-steroidal anti-inflammatory drugs)
• Tubocurarine

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

Most common side effects of AMLOKIND H Tablet are:

• Weakness, pain, fatigue, malaise
• Headache, dizziness, vertigo, nervousness, depression
• Increased muscle tone, decreased sensations
• Anxiety
• Low blood pressure, fainting, palpitation, irregular rhythm, increased heart rate, chest pain, heart attack
• Dry mouth, thirst, loss of appetite, nausea, vomiting, abdominal pain, diarrhoea or constipation, passing of gas, weight changes
• Increased sweating, skin discolouration
• Muscle cramps, back pain, pain in joints
• Abnormal vision

Please contact your physician immediately if you have

• allergic reactions (swelling of the face, mouth, larynx (voice box), itching and rash);
• severe light-headedness or fainting;
• angioneurotic oedema (red, burning, itching areas on skin near eyes, lips, hands, feet and inside of throat, hoarseness of voice, difficulty in breathing);
• low levels of serum potassium;
• severe skin allergies such as blisters on skin, mouth, lips, eyes and genitals (commonly called Steven Johnsons syndrome).

This is not a comprehensive list of side effects. Consult your doctor to know more about other possible side effects.

If you have taken an overdose of AMLOKIND H Tablet, please contact your doctor immediately.

Symptoms of overdose of Amlodipine may include the following:

• Dizziness
• Light headedness
• Fainting, weakness
• Cool and clammy skin
• Hypotension (low blood pressure)
• Loss of consciousness

Symptoms of overdose of Hydrochlorothiazide may include the following:

• Dehydration
• Diarrhoea or constipation, abdominal pain
• Dizziness, fainting
• Electrolyte imbalance (hypokalaemia (low levels of potassium in blood), hypochloraemia (low levels of chloride ions in blood, hyponatremia (low levels of sodium in the blood)
• Lethargy
• Nausea
• Weakness

1. How should AMLOKIND H Tablet be stored?

AMLOKIND H Tablet should be stored below 30C. Keep the medicine away from sunlight and do not freeze the medicine. Keep the medicine out of reach from children.

2. Can I drive while taking AMLOKIND H Tablet?

AMLOKIND H Tablet causes drowsiness, dizziness and headache in some individuals. Avoid driving if you are taking AMLOKIND H Tablet.

3. Should I follow any special dietary instructions while taking AMLOKIND H Tablet?

Do not take grapefruit or grapefruit juice while on AMLOKIND H Tablet. Apart from this, there are no dietary restrictions if you are taking AMLOKIND H Tablet.

4. Can I drink alcohol while taking AMLOKIND H Tablet?

No, it is not advisable to consume alcohol while on AMLOKIND H Tablet as it can make you dizzy, sleepy or tired.

5. Is AMLOKIND H Tablet addictive?

No, AMLOKIND H Tablet is not addictive. But do not take it without consulting your doctor.