GRANIFORCE Injection is used to prevent nausea and vomiting in patients undergoing chemotherapy treatment.

GRANIFORCE Injection may also be prescribed for other conditions as determined by the doctor.

GRANIFORCE Injection is a serotonin receptor antagonist, which works by blocking the serotonin activity. It inhibits certain receptors present in the medullary chemoreceptor zone and the gastrointestinal tract. Thus, it reduces chemotherapy-induced nausea and vomiting.

The dosage and the drug form depend on the age, weight and medical condition of an individual. GRANIFORCE Injection is available as injection, tablet and syrup.

• GRANIFORCE Injection injection should be administered only under medical supervision.
• Swallow the tablet whole. Do not crush or chew the tablet.
• Use a measuring cup while taking each dose of GRANIFORCE Injection syrup.

If you miss a dose of GRANIFORCE Injection , please use it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for the missed dose.

Drugs that interact with GRANIFORCE Injection include the following:

• Acetaminophen
• Amitriptyline
• Brompheniramine
• Dextromethorphan
• Doxylamine
• Guaifenesin
• Phenylephrine
• Sumatriptan

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

The following are the most common side effects of GRANIFORCE Injection :

• Diarrhoea
• Constipation
• Stomach pain
• Weakness
• Headache
• Increased blood pressure

The following are the severe side effects and you may require immediate medical attention:

• Severe dizziness
• Chest pain
• Fast or irregular heartbeat

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

• Avoid using the medicine if you are allergic to GRANIFORCE Injection or similar drugs.
• Seek doctor’s advice before taking any other drug or herbal products while on GRANIFORCE Injection .
• Avoid GRANIFORCE Injection during pregnancy or breastfeeding because the safe use of the drug is not yet established.
• Do not exceed the dose more than what is prescribed.
• Do not stop using the medication abruptly unless instructed by the doctor. Discontinuing the medication suddenly may cause the illness to return.

• Tell your doctor if you have any history of kidney impairment, heart diseases or problems.
• Inform the doctor if you have undergone any stomach or intestinal surgeries.
• Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
• Tell your doctor if you are allergic to GRANIFORCE Injection or any similar drugs.

1. What are the overdose symptoms of GRANIFORCE Injection injection?

The overdose symptoms of GRANIFORCE Injection injection include headache, skin rash, hallucinations, dizziness, fever, tremor, incoordination and persistent vomiting. Please consult your doctor if you experience any of the above symptoms.

2. How should GRANIFORCE Injection tablet be stored?

Store the drug at room temperature (15 – 30^OC) and avoid exposure to sunlight and moisture.

3. What are the other formulations available for GRANIFORCE Injection ?

GRANIFORCE Injection medicine is available as injection, syrup and tablet.

4. Do I need to be monitored for any laboratory parameters while using GRANIFORCE Injection ?

Monitoring of heart function and kidney function is important while using GRANIFORCE Injection .

5. Is it safe to alter the dose of GRANIFORCE Injection ?

No. Do not alter the dose of GRANIFORCE Injection medicine. Consult your doctor if you have any problem with the prescribed dose.