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What is ROSUMAC?
- ROSUMAC contains Aspirin, Clopidogrel and Rosuvastatin
- Aspirin and Clopidogrel belongs to a group of medicines called antiplatelet agents that help to prevent your blood cells sticking together and forming a blood clot
- Rosuvastatin belongs to a group of medicines called statins
CONSUMER MEDICINE INFORMATION
THERAPEUTIC USES
WARNING & PRECAUTIONS
INTERACTIONS
DIRECTIONS FOR USE
SIDE EFFECTS
MORE INFORMATION
What ROSUMAC is used for?
It is used to prevent,
- blood clots which can lead to atherothrombotic events such as stroke, heart attack, or death
- atherosclerosis
- peripheral arterial disease
- atrial fibrillation
- high cholesterol level
Talk to your doctor before taking this medicine, If you
- are allergic to Aspirin, , Rosuvastatin or to any of the ingredients in this medicine
- are allergic to other salicylates or nonsteroidal anti-inflammatory drugs (NSAIDs)
- have had an asthma attack or swelling of some parts of the body
- have or ever had an ulcer in your stomach or small intestine
- ever had the problem of your blood not clotting properly
- are suffering from gout
- have severe liver or kidney problems
- suffer from blood disorder that makes you prone to internal bleeding
- have planned for a surgery
- have had a clot in an artery of your brain (ischemic stroke)
- have had repeated or unexplained muscle aches or pains
- have thyroid problem
- are over 70 years of age
- have severe respiratory failure
- consume alcohol
Tell your doctor, if you are taking medicines for:
- thinning of the blood/prevention of clots (e.g. warfarin, heparin, phenindione and clopidogrel)
- organ rejection after transplantation (e.g. ciclosporin, tacrolimus)
- high blood pressure (e.g. diuretics and ACE-inhibitors)
- regulation of the heart beat (digoxin)
- manic-depressive illness (lithium)
- pain and inflammation (e.g. anti-inflammatory medicines such as ibuprofen, or steroids)
- gout (e.g. probenecid)
- epilepsy (valproate, phenytoin)
- glaucoma (acetazolamide)
- cancer or rheumatoid arthritis (e.g. methotrexate)
- diabetes (e.g. glibenclamide)
- depression (selective serotonin re-uptake inhibitors (SSRIs) such as sertraline or paroxetine or moclobemide)
- iron salts (for treatment of iron deficiency anaemia)
- darbonates (treatment of peptic ulcer and reflux)
- alkali hydroxides (antacids)
- heparin or any other injectable medicine used to reduce blood clotting, ticlopidine, other antiplatelet agent
- a selective serotonin reuptake inhibitor (including but not restricted to fluoxetine or fluvoxamine), medicines usually used to treat depression
- omeprazole or esomeprazole, medicines to treat upset stomach
- fluconazole or voriconazole, medicines to treat fungal infections
- carbamazepine, a medicine to treat some forms of epilepsy
- repaglinide, medicine to treat diabetes
- paclitaxel, medicine to treat cancer
- fibrates (such as gemfibrozil, fenofibrate) or any other medicine used to lower cholesterol (such as ezetimibe)
- erythromycin (an antibiotic)
- an oral contraceptive (the pill)
- HIV or hepatitis C infection such as ritonavir, lopinavir
- Always take this medicine exactly as your doctor has told you
- You can take ROSUMAC orally with or without food, and at the same time each day
If you take more ROSUMAC
- Contact your doctor or the nearest hospital emergency department because of the increased risk of bleeding.
If you forget to take ROSUMAC
- If you forget to take a dose of tablet but remember within 12 hours of your usual time, take your tablet straightaway and then take your next tablet at the usual time
- If you forget for more than 12 hours, simply take the next single dose at the usual time
- Do not take a double dose to make up for a forgotten tablet
If you stop taking ROSUMAC
- Do not stop the treatment unless your doctor tells you so
Like all medicines, this medicine also can cause side effects, although not everybody gets them.
SERIOUS
COMMON
UNCOMMON
RARE
VERY RARE
- sudden wheezing, swelling of your lips, face or body, rash, fainting or difficulties swallowing (severe allergic reaction)
- reddening of the skin with blisters or peeling and may be associated with a high fever and joint pains
- unusual bleeding, such as coughing up blood, blood in your vomit or urine, or black stools
- fever, signs of infection or extreme tiredness
- signs of liver problems such as yellowing of the skin and/or the eyes (jaundice)
- indigestion
- increased tendency for bleeding
- bleeding in the stomach or bowels, bruising, haematoma (unusual bleeding or bruising under the skin), nose bleed, blood in the urine
- headache, stomach pain, constipation, feeling sick, muscle pain, feeling weak, dizziness.
- an increase in the amount of protein in the urine
- hives
- runny nose
- breathing difficulty
- headache
- stomach ulcer
- vomiting
- nausea
- constipation
- excessive gas in stomach or intestines
- rashes, itching, dizziness, sensation of tingling and numbness
- severe bleeding in the stomach or intestines, brain hemorrhage; altered number of blood cells
- cramps in the lower respiratory tract, asthma attack
- inflammation in the blood vessels
- severe rash
- hypersensitivity reactions, such as swelling of e.g. lips, face or body, or shock
- abnormal heavy or prolonged menstrual periods
- vertigo
- enlarged breasts in males
- muscle damage in adults such as any unusual aches or pains in your muscles
- a severe stomach pain (inflamed pancreas)
- increase in liver enzymes in the blood
- bleeding or bruising more easily than normal due to low level of blood platelets
- fever, breathing difficulties sometimes associated with cough
- generalized allergic reactions (for example, overall sensation of heat with sudden general discomfort until fainting), swelling in the mouth; blisters of the skin; skin allergy; sore mouth (stomatitis)
- decrease in blood pressure
- confusion, hallucinations
- joint pain, muscular pain
- changes in taste of food
- liver problems such as Jaundice, hepatitis (an inflamed liver), traces of blood in your urine, damage to the nerves of your legs and arms (such as numbness), joint pain, memory loss and breast enlargement in men (gynaecomastia)
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