Talk to your doctor before taking TIDOMET CR, if you:

• are allergic (hypersensitive) to carbidopa or levodopa or any of the other ingredients of TIDOMET CR
• have ever had skin cancer or you have any unusual moles which have not been examined by your doctor
• have a condition called ‘narrow-angle glaucoma’ that may cause a sudden buildup of pressure in the eye
• have a history of fits (convulsions)
• have had an ulcer in your gut (called ‘duodenal’ or ‘peptic ulcer’) or have vomited blood
• have had a heart attack, heart beat problems, circulation or breathing problems
• have had kidney, liver or hormonal problems
• have had depression or other mental problems
• have a condition called ‘chronic wide-angle glaucoma’ that may cause a buildup of pressure in the eye
• sometimes have sudden sleep attacks or sometimes feel very sleepy

• It is unknown whether TIDOMET CR will pass into human milk
• Ask your doctor for advice before taking any medicine, if you are pregnant or planning to become pregnant or are breast-feeding

• TIDOMET CR is not suitable for children under the age of 18 years

• TIDOMET CR can also make you sleepy or cause sudden sleep attacks. If this happens to you, you must not drive or use tools or machines
• Do not drive or use tools or machines if you get these effects your doctor will tell you if you can start driving again if these attacks stop

• allergic reaction, the signs may include hives (nettle rash), itching, and rash, swelling of your face, lips, tongue or throat
• breathing or swallowing
• chest pain
• irregular heart beat or palpitations
• dizziness on standing-up quickly
• bleeding from your gut which may be seen as blood in your faeces or darkened faeces (gastro-intestinal bleeding)
• blood problems, the signs may include pale skin (pallor), tiredness, fever, sore throat or mild bruising and prolonged bleeding after injury
• stiff muscles, high fever
• mental changes including delusions, hallucinations and depression
• fits (convulsions)

• abnormal movements such as twitching or spasms (which may or may not be like your Parkinsons symptoms)
• nausea

• fainting, anorexia, high blood pressure
• inflammation of the veins, being sick (vomiting) diarrhoea, discoloration of urine, sweat or saliva
• dream abnormalities, confusion, feeling agitated, shortness of breath, hair loss

• severe abnormal involuntary movements (dyskinesia’s), mood swings
• strong impulse to gamble excessively despite serious personal or family consequences
• an increased sexual drive
• uncontrollable excessive shopping or spending
• binge eating (eating large amounts of food in a short time period) or compulsive eating (eating more food than normal and more than is needed to satisfy your hunger)

NA

Parkinsons disease is a long-term illness where:

• you become slow and unsteady
• your muscles feel stiff
• you may develop shaking or trembling (called ‘tremor’)

• Keep this medicine out of reach of children
• Store at room temperature (15-25ºC)
• Do not use TIDOMET CR after the expiry date