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What is TWICHEK DSR?
- TWICHEK DSR contains domperidone and rabeprazole
- Domperidone belongs to a group of medicines called dopamine antagonists
- Rabeprazole belongs to a group of medicines called Proton Pump Inhibitors (PPIs). It acts by reducing the amount of acid made by the stomach
CONSUMER MEDICINE INFORMATION
THERAPEUTIC USES
WARNING & PRECAUTIONS
INTERACTIONS
DIRECTIONS FOR USE
SIDE EFFECTS
MORE INFORMATION
What TWICHEK DSR is used for?
It is used to treat,
- nausea and vomiting
- ulcer in the upper part of the intestine (duodenal ulcer) and benign stomach ulcer
- Gastro-Oesophageal Reflux Disease (GERD) with or without ulcer
- Zollinger-Ellison Syndrome
- Helicobacter pylori infection with combination of antibiotics
Talk to your doctor before taking this medicine, if you:
- are allergic to domperidone, rabeprazole or any of the other ingredients in this medicine
- have black, tarry bowel motions (stools) or notice blood in your bowel motions. This could be a sign of bleeding in the stomach or intestines
- have a blockage or tear in your intestines
- have a tumor of the pituitary gland called a prolactinoma
- have a moderate or severe liver and kidney disease
- have or had heart failure
Talk to your doctor if you are taking medicines such as,
- oral ketoconazole, fluconazole or voriconazole used for fungal infections
- erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine used for bacterial infections
- heart problems or high blood pressure (e.g., amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil)
- haloperidol, pimozide, sertindole used for psychoses
- citalopram, escitalopram used for depression
- gastro-intestinal disorders (e.g., cisapride, dolasetron, prucalopride)
- mequitazine, mizolastine used for allergy
- halofantrine used for malaria
- protease inhibitors used for AIDS/HIV
- toremifene, vandetanib, vincamine, erlotinib used for cancer
- Always take this medicine exactly as your doctor has told you
- For oral use only
- Take this medicine must be swallowed with a glass of water
- Take this medicine before meals
If you take more TWICHEK DSR
- If you take more TWICHEK DSR, consult your doctor immediately
If you forget to take TWICHEK DSR
- If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose
If you stop taking TWICHEK DSR
- Do not stop taking this medicine without first talking to your doctor
Like all medicines, these medicines can have side effects, although not everybody gets them.
SERIOUS
COMMON
UNCOMMON
RARE
VERY RARE
Domperidone:
- swelling of the hands, feet, ankles, face, lips or throat which may cause difficulty in swallowing or breathing
- irregular eye movements, unusual movements of the tongue, and abnormal posture such as a twisted neck, trembling and muscle stiffness
- very fast or unusual heartbeat
Rabeprazole:
- sudden wheezing, swelling of your lips, face or body, rash, fainting or difficulties swallowing (severe allergic reaction)
- yellow skin, dark urine and tiredness which can be symptoms of liver problems
- reddening of the skin with blisters or peeling and may be associated with a high fever and joint pains
- severe blisters and bleeding in the lips, eyes, mouth, nose and genitals
Domperidone:
- dry mouth
Rabeprazole:
- cough, sore throat (inflammation of the pharynx), runny nose
- nausea, vomiting, abdominal pain, diarrhoea, constipation, wind (flatulence)
- back pain, non-specific pain
- weakness or loss of strength, flu like symptoms
- sleeplessness, headache, dizziness
- benign polyps in the stomach
Domperidone:
- anxiety
- loss of interest in sex or diminished interest in sex
- sleepiness or headache
- diarrhoea, rash or itchiness
- painful or tender breasts, or discharge from breasts
- a general feeling of weakness
Rabeprazole:
- inflammation of the bronchial tubes (bronchitis), inflammation of the sinuses (sinusitis).
- indigestion, belching
- increased liver enzymes, which is measured by blood tests
- fracture of the hip, wrist or spine
Rabeprazole:
- blood problems such as reduced number of white cells or platelets. This can cause weakness, bruising or make infections more likely
- loss of appetite
- depression
- visual disturbance
- increased weight
Disclaimer:
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
