Talk to your doctor before taking this medicine, if you:

• are allergic to this medicine
• are suffering from liver disease
• have cardiomyopathy, irregular heartbeat, slow heart rate or an abnormality of electrocardiogram (ECG)

VFEND contains lactose If you have been told by your doctor that you have an intolerance to some sugars, tell your doctor before taking this medicine.

• VFEND must not be used during pregnancy, unless indicated by your doctor. Effective contraception must be used in women of childbearing potential
• If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine

• VFEND should not be given to children younger than 2 years of age

• VFEND may cause blurring of vision or uncomfortable sensitivity to light. While affected, do not drive or operate any tools or machines

• rash
• jaundice
• pancreatitis
• bleeding in the eye

• inflammation of the sinuses, inflammation of the gums, chills, weakness
• low blood cell count
• low blood sugar, low blood potassium, low sodium in the blood
• anxiety, depression, confusion, agitation, inability to sleep, hallucinations
• seizures, tremors or uncontrolled muscle movements, tingling or abnormal skin sensations, increase in muscle tone, sleepiness, dizziness
• heart rhythm problems including very fast heartbeat, very slow heartbeat, fainting
• low blood pressure, inflammation of a vein (which may be associated with the formation of a blood clot)
• acute breathing difficulty, chest pain, swelling of the face (mouth, lips and around eyes), fluid accumulation in the lungs
• constipation, indigestion
• jaundice, inflammation of the liver and liver injury
• skin rashes which may lead to severe blistering and peeling of the skin characterized by a flat, red area on the skin that is covered with small confluent bumps, redness of the skin
• itchiness
• hair loss
• back pain
• kidney failure, blood in the urine, changes in kidney function tests

• flu-like symptoms, irritation and inflammation of the gastrointestinal tract, inflammation of the gastrointestinal tract causing antibiotic associated diarrhoea, inflammation of the lymphatic vessels
• inflammation of the thin tissue that lines the inner wall of the abdomen and covers the abdominal organ
• enlarged lymph glands (sometimes painful), failure of blood marrow, increased eosinophil
• depressed function of the adrenal gland, underactive thyroid gland
• abnormal brain function, parkinson-like symptoms, nerve injury resulting in numbness, pain, tingling or burning in the hands or feet
• problems with balance or coordination
• swelling of the brain
• double vision, serious conditions of the eye including: pain and inflammation of the eyes and eyelids, abnormal eye movement, damage to the optic nerve resulting in vision impairment, optic disc swelling
• decreased sensitivity to touch
• abnormal sense of taste
• hearing difficulties, ringing in the ears, vertigo
• inflammation of certain internal organs- pancreas and duodenum, swelling and inflammation of the tongue
• enlarged liver, liver failure, gallbladder disease, gallstones
• joint inflammation, inflammation of the veins under the skin (which may be associated with the formation of a blood clot)
• inflammation of the kidney, proteins in the urine, damage to the kidney
• very fast heart rate or skipped heartbeats, sometimes with erratic electrical impulses
• abnormal electrocardiogram
• blood cholesterol increased, blood urea increased
• allergic skin reactions (sometimes severe), including life-threatening skin condition that causes painful blisters and sores of the skin and mucous membranes, especially in the mouth, inflammation of the skin, hives, sunburn or severe skin reaction following exposure to light or sun, skin redness and irritation, red or purple discoloration of the skin which may be caused by low platelet count, eczema
• infusion site reaction
• allergic reaction or exaggerated immune response

• overactive thyroid gland
• deterioration of brain function that is a serious complication of liver disease
• loss of most fibres in the optic nerve, clouding of the cornea, involuntary movement of the eye
• bullous photosensitivity
• a disorder in which the bodys immune system attacks part of the peripheral nervous system
• heart rhythm or conduction problems (sometimes life threatening)
• life threatening allergic reaction
• disorder of blood clotting system
• small dry scaly skin patches, sometimes thick with spikes or horns

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• Keep this medicine out of reach of children
• Store at room temperature (15-25C)
• Do not use this medicine after the expiry date