Talk to your doctor before taking ZURIG 40MG, if you:

• have heart problems
• have liver disease or liver function test abnormalities
• are being treated for high uric acid levels because of Lesch-Nyhan syndrome (a rare inherited condition in which there is too much uric acid in the blood)
• have thyroid problem
• have kidney problem

• ZURIG 40MG should not be used during pregnancy
• You should not use ZURIG 40MG if you are breast feeding, or if you are planning to breastfeed
• Consult your doctor for advice

• Do not give this medicine to children under the age of 18 because the safety and efficacy have not been established

• You may experience dizziness, sleepiness, blurred vision and numbness or tingling sensation during treatment
• Do not drive or operate machines if affected

• anaphylactic reactions such as hives, rash, and itching, chest pain or chest tightness, difficulty in breathing, swelling of your face or tongue
• potentially life-threatening skin rashes characterized by formation of blisters and shedding of the skin and inner surfaces of body cavities, e.g. mouth and genitals
• painful ulcers in the mouth and/or genital areas, accompanied by fever, sore throat and fatigue
• generalised skin rashes

• abnormal liver test results
• diarrhoea, headache, rash, nausea
• increase in gout symptoms
• localized swelling due to retention of fluids in tissues (oedema)

• decreased appetite, change in blood sugar levels (diabetes)
• loss of sex drive
• difficulty in sleeping
• dizziness, numbness, tingling, reduced or altered sensation (hypoaesthesia, hemiparesis or paraesthesia), altered or reduced sense of taste (hyposmia)
• abnormal ECG heart tracing, irregular or rapid heartbeats, feeling your heart beat (palpitation)
• hot flushes or flushing (e.g. redness of the face or neck), increased blood pressure, bleeding (hemorrhage, seen only in patients taking chemotherapy for blood disorders)
• cough, shortness of breath, chest discomfort or pain, inflammation of nasal passage and/or throat (upper respiratory tract infection), bronchitis
• dry mouth, abdominal pain, heartburn/indigestion, constipation, more frequent passing of stools, vomiting
• itching, hives, skin inflammation, skin discoloration, small red or purple spot on the skin
• muscle cramp, muscle weakness, pain/ache in muscles/joints
• fatigue, chest pain, chest discomfort
• stones in the gallbladder or in bile ducts (cholelithiasis)
• increase in blood thyroid stimulating hormone (TSH) level
• changes in blood chemistry or amount of blood cells or platelets (abnormal blood test results)
• kidney stones

• severe swelling around the lips, eyes, genitals, hands, feet or tongue, with possible sudden difficulty in breathing
• reddening of the skin (erythema)
• nervousness, feeling thirsty
• ringing in the ears
• blurred vision, change in vision
• hair loss
• mouth ulceration
• inflammation of the pancreas
• increased sweating
• abnormally low blood cell counts (white or red blood cells or platelets)
• urgent need to urinate
• changes or decrease in urine amount due to inflammation in the kidneys (tubulointerstitial nephritis)
• inflammation of the liver (hepatitis), yellowing of the skin (jaundice), liver damage
• increased level of creatine phosphokinase in blood (an indicator of muscle damage)

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• Keep this medicine out of reach of children
• Do not use this medicine after the expiry date
• Store at room temperature (15-25C)